WHO Classification of Lymphomas

Feb/98

B-cell neoplasms/lymphomas

B-cell lymphoblastic leukemia/lymphoma

Mature B-cell Neoplasms

B-cell CLL/ small lymphocytic lymphoma

B-cell prolymphocytic leukemia

lymphoplasmacytic lymphoma ( +/- Waldenström’s)

Mantle cell lymphoma

Follicular lymphoma, grades 1 and 2

Marginal zone B-cell lymphoma of MALT type (+/- monocytoid B-cells)

Nodal Marginal zone B-cell lymphoma (+/- monocytoid B-cells)

Splenic marginal zone cell lymphoma

Diffuse large B-cell lymphoma

Subtypes: mediastinal (thymic), intravascular, primary effusion lymphoma

Burkitt lymphoma

Hairy cell leukemia

Plasmacytoma / Plasma cell myeloma

T-cell neoplasms/lymphomas

Precursor T-lymphoblastic lymphoma/leukemia

Mature T-cell Neoplasms

Predominantly leukemic/disseminated

T-CLL

T-cell prolymphocytic leukemia, T-cell large granular lymphocytic leukemia

NK-cell leukemia

Sezary syndrome

Adult T-cell leukemia/lymphoma (HTLV 1+)

Hepatosplenic g/d T-cell lymphoma

Predominantly nodal

Angioimmunoblastic T-cell lymphoma                                       

Systemic anaplastic large cell lymphoma (T and Null types), CD30+

Peripheral T-cell lymphoma unspecified

Predominantly extranodal

NK/T-cell lymphoma, nasal-type (angiocentric lymphoma)

Mycosis fungoides

Primary cutaneous anaplastic large cell lymphoma

Subcutaneous panniculitis-like T-cell lymphoma

Intestinal T-cell (+/- enteropathy)